![]() Until about a decade later, when Ferguson joined one of the of original MASCIS centers, the Ohio State University (OSU). MASCIS did produce important standards that have since been adopted by many SCI labs, like the Basso, Beattie, Bresnahan (BBB) score to measure outcomes and controlled ways to model different injuries, but with no promise of a therapy to push on into the clinic for human trials, the data went dark, physical copies seemingly destined to fade away in the depths of file drawers and storage bins across the country.ĪHEAD OF THE CURVE | Adam Ferguson, University of California San Francisco, has new ideas for old data in preclinical spinal cord injury research. Despite the years of effort and coordination between the different groups involved, the drug results were ambiguous and the trials were stopped. Led by New York University Professor Wise Young (who later relocated, with his laboratory archive, to Rutgers) and run like a clinical randomized controlled trial, MASCIS tested potential drugs to treat SCI in rats at eight different US laboratories. ![]() That storage unit likely contains the complete set of records from an ambitious preclinical SCI project known as MASCIS, the Multicenter Animal Spinal Cord Injury Study, which was funded by the NIH from 1993 to 1996. ![]()
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